Cellosaurus cell line DLD-1 clone D (CVCL

Cellosaurus DLD-1 clone D (CVCL_V012)

Cross-references
Cell line name	DLD-1 clone D
Synonyms	DLD-1 Clone D; Clone D; CLONE D; CLONE_D
Accession	CVCL_V012
Resource Identification Initiative	To cite this cell line use: DLD-1 clone D (RRID:CVCL_V012)
Comments	Population: Caucasian. Doubling time: 20 hours (PubMed=427742). Derived from site: In situ; Colon; UBERON=UBERON_0001155. Cell type: Epithelial cell of colon; CL=CL_0011108.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser241Phe (c.722C>T); ClinVar=VCV000012359; Zygosity=Unspecified (PubMed=7651727).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0248 (DLD-1)
Sex of cell	Male
Age at sampling	67Y
Category	Cancer cell line
Publications	PubMed=427742 Dexter D.L., Barbosa J.A., Calabresi P. N,N-dimethylformamide-induced alteration of cell culture characteristics and loss of tumorigenicity in cultured human colon carcinoma cells. Cancer Res. 39:1020-1025(1979) PubMed=7247963; DOI=10.1016/0006-2952(81)90167-2 Crabtree G.W., Dexter D.L., Stoeckler J.D., Savarese T.M., Ghoda L.Y., Rogler-Brown T.L., Calabresi P., Parks R.E. Jr. Activities of purine-metabolizing enzymes in human colon carcinoma cell lines and xenograft tumors. Biochem. Pharmacol. 30:793-798(1981) PubMed=7651727 Kastrinakis W.V., Ramchurren N., Rieger K.M., Hess D.T., Loda M., Steele G., Summerhayes I.C. Increased incidence of p53 mutations is associated with hepatic metastasis in colorectal neoplastic progression. Oncogene 11:647-652(1995)
Cell line databases/resources	cancercelllines; CVCL_V012 ColonAtlas; CLONE_D
Encyclopedic resources	Wikidata; Q54831157
Polymorphism and mutation databases	Cosmic; 1374643
Entry history
Entry creation	16-Apr-2014
Last entry update	19-Dec-2024
Version number	11