ID   K107-Ep
AC   CVCL_UZ33
SY   K107
DR   Wikidata; Q94334180
RX   PubMed=12077343;
WW   https://dermatology.bwh.harvard.edu/docs/Cell-Culture-Core-Cell-Lines.pdf
CC   Senescence: Senesces at 55 PDL (PubMed=12077343).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Gly101Trp (c.301G>T) (p.Arg115Leu, c.344G>T); ClinVar=VCV000009412; Zygosity=Heterozygous (PubMed=12077343).
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   52Y
CA   Finite cell line
DT   Created: 25-02-19; Last updated: 19-12-24; Version: 10
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RX   PubMed=12077343; DOI=10.1128/mcb.22.14.5157-5172.2002; PMCID=PMC139780;
RA   Rheinwald J.G., Hahn W.C., Ramsey M.R., Wu J.Y., Guo Z.-Y., Tsao H.,
RA   De Luca M., Catricala C., O'Toole K.M.;
RT   "A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence
RT   mechanism that limits replicative potential independent of telomere
RT   status.";
RL   Mol. Cell. Biol. 22:5157-5172(2002).
//