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Cellosaurus CHO SH-87 (CVCL_UZ06)

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Cell line name CHO SH-87
Synonyms SH-87; SH87
Accession CVCL_UZ06
Resource Identification Initiative To cite this cell line use: CHO SH-87 (RRID:CVCL_UZ06)
Comments Characteristics: Transfected with a tricistronic vector utilizing internal ribosome entry site (IRES) elements to express the light chain (LC), heavy chain (HC) and a neo selection marker from one transcript.
Characteristics: Produces an anti-ERBB2 monoclonal antibody.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Omics: Genome sequenced.
Omics: Metabolome analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=22024589; DOI=10.1016/j.jbiotec.2011.09.023
Ho S.C.-L., Bardor M., Feng H.-T., Mariati X., Tong Y.W., Song Z.-W., Yap M.G.-S., Yang Y.-S.
IRES-mediated tricistronic vectors for enhancing generation of high monoclonal antibody expressing CHO cell lines.
J. Biotechnol. 157:130-139(2012)

PubMed=28544881; DOI=10.1016/j.cels.2017.04.009
Yusufi F.N.K., Lakshmanan M., Ho Y.-S., Loo B.L.-W., Ariyaratne P., Yang Y.-S., Ng S.K., Tan T.R.-M., Yeo H.C., Lim H.L., Ng S.W., Hiu A.-P., Chow C.P., Wan C., Chen S.-W., Teo G., Song G., Chin J.-X., Ruan X.-A., Sung K.W.-K., Hu W.-S., Yap M.G.-S., Bardor M., Nagarajan N., Lee D.-Y.
Mammalian systems biotechnology reveals global cellular adaptations in a recombinant CHO cell line.
Cell Syst. 4:530-542.e6(2017)

Cross-references
Encyclopedic resources Wikidata; Q93451260
Metabolomic databases MetaboLights; MTBLS493
Entry history
Entry creation25-Feb-2019
Last entry update10-Sep-2024
Version number10