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Cellosaurus BsB8 (CVCL_UZ01)

[Text version]
Cell line name BsB8
Synonyms Bs-1B8
Accession CVCL_UZ01
Resource Identification Initiative To cite this cell line use: BsB8 (RRID:CVCL_UZ01)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03072; JC polyomavirus large T antigen.
Transformant: NCBI_TaxID; 10632; JC polyomavirus (JCPyV).
Disease Mouse neuroblastoma (NCIt: C21993)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: JCV T-Ag transgenic.
Originate from same individual CVCL_UY99 ! Bs1A
CVCL_UZ00 ! BsB7
CVCL_UZ02 ! BsB13
CVCL_UZ03 ! BsB14
Category Cancer cell line
Publications

PubMed=10936089; DOI=10.1006/viro.2000.0450
Krynska B., Del Valle L., Gordon J., Otte J., Croul S., Khalili K.
Identification of a novel p53 mutation in JCV-induced mouse medulloblastoma.
Virology 274:65-74(2000)

PubMed=11877394; DOI=10.1074/jbc.M110885200
Lassak A., Del Valle L., Peruzzi F., Wang J.-Y., Enam S., Croul S., Khalili K., Reiss K.
Insulin receptor substrate 1 translocation to the nucleus by the human JC virus T-antigen.
J. Biol. Chem. 277:17231-17238(2002)

PubMed=22207898; DOI=10.1177/1947601911424578; PMCID=PMC3218408
Uleri E., Beltrami S., Gordon J., Dolei A., Sariyer I.K.
Extinction of tumor antigen expression by SF2/ASF in JCV-transformed cells.
Genes Cancer 2:728-736(2011)

PubMed=30108683; DOI=10.18632/genesandcancer.174; PMCID=PMC6086003
Donadoni M., Sariyer R., Wollebo H.S., Bellizzi A., Sariyer I.K.
Viral tumor antigen expression is no longer required in radiation-resistant subpopulation of JCV induced mouse medulloblastoma cells.
Genes Cancer 9:130-141(2018)

Cross-references
Encyclopedic resources Wikidata; Q93432197
Entry history
Entry creation25-Feb-2019
Last entry update10-Sep-2024
Version number4