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Cellosaurus Luc63.2.22 (CVCL_UW14)

[Text version]
Cell line name Luc63.2.22
Synonyms Luc63; MuLuc63
Accession CVCL_UW14
Resource Identification Initiative To cite this cell line use: Luc63.2.22 (RRID:CVCL_UW14)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-5950.
Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the humanized elotuzumab (HuLuc63; Empliciti) therapeutic antibody. It was developed for the treatment of multiple myeloma.
Monoclonal antibody isotype: IgG2a.
Monoclonal antibody target: UniProtKB; Q9NQ25; Human SLAMF7/CD319.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_3940 (NS0)
Category Hybridoma
Publications

Patent=US8461306
Williams M., Tso J.Y., Landolfi N.F., Powers D.B., Liu G.
Therapeutic use of anti-CS1 antibodies.
Patent number US8461306, 11-Jun-2013

Cross-references
Encyclopedic resources Wikidata; Q95983312
Entry history
Entry creation25-Feb-2019
Last entry update21-Mar-2023
Version number5