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Cellosaurus MCF-7 M21 (CVCL_UU88)

[Text version]
Cell line name MCF-7 M21
Synonyms M21
Accession CVCL_UU88
Resource Identification Initiative To cite this cell line use: MCF-7 M21 (RRID:CVCL_UU88)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 2640; CYP3A7.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=1727631; DOI=10.1016/0003-9861(92)90061-Z
Kitamura R., Sato K., Sawada M., Itoh S., Kitada M., Komori M., Kamataki T.
Stable expression of cytochrome P450IIIA7 cDNA in human breast cancer cell line MCF-7 and its application to cytotoxicity testing.
Arch. Biochem. Biophys. 292:136-140(1992)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UU88
Encyclopedic resources Wikidata; Q95986060
Entry history
Entry creation25-Feb-2019
Last entry update10-Sep-2024
Version number9