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Cellosaurus MCL-2 (CVCL_UU64)

[Text version]
Cell line name MCL-2
Accession CVCL_UU64
Resource Identification Initiative To cite this cell line use: MCL-2 (RRID:CVCL_UU64)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 2610; CYP2A6.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 3401; EPHX1.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_UU62 (AHH-1 TK+/- L3)
Sex of cell Male
Age at sampling 33Y
Category Transformed cell line
Publications

PubMed=2706743; DOI=10.1093/carcin/10.5.885
Davies R.L., Crespi C.L., Rudo K., Turner T.R., Langenbach R.
Development of a human cell line by selection and drug-metabolizing gene transfection with increased capacity to activate promutagens.
Carcinogenesis 10:885-891(1989)

PubMed=8236284; DOI=10.1016/0300-483X(93)90062-W
Crespi C.L., Langenbach R., Penman B.W.
Human cell lines, derived from AHH-1 TK+/- human lymphoblasts, genetically engineered for expression of cytochromes P450.
Toxicology 82:89-104(1993)

Cross-references
Encyclopedic resources Wikidata; Q95986960
Entry history
Entry creation25-Feb-2019
Last entry update10-Sep-2024
Version number9