ID   MCL-1
AC   CVCL_UU63
DR   Wikidata; Q95986959
RX   Patent=US5429948;
RX   PubMed=2706743;
RX   PubMed=8236284;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9562.
CC   Population: Caucasian.
CC   Transfected with: HGNC; 2610; CYP2A6.
CC   Transfected with: HGNC; 3401; EPHX1.
CC   Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_UU62 ! AHH-1 TK+/- L3
SX   Male
AG   33Y
CA   Transformed cell line
DT   Created: 25-02-19; Last updated: 05-10-23; Version: 8
//
RX   Patent=US5429948;
RA   Crespi C.L., Penman B.W., Davies R.L.;
RT   "Human cell line stably expressing 5 cDNAS encoding procarcinogen-
RT   activating enzymes and related mutagenicity assays.";
RL   Patent number US5429948, 04-Jul-1995.
//
RX   PubMed=2706743; DOI=10.1093/carcin/10.5.885;
RA   Davies R.L., Crespi C.L., Rudo K., Turner T.R., Langenbach R.;
RT   "Development of a human cell line by selection and drug-metabolizing
RT   gene transfection with increased capacity to activate promutagens.";
RL   Carcinogenesis 10:885-891(1989).
//
RX   PubMed=8236284; DOI=10.1016/0300-483X(93)90062-W;
RA   Crespi C.L., Langenbach R., Penman B.W.;
RT   "Human cell lines, derived from AHH-1 TK+/- human lymphoblasts,
RT   genetically engineered for expression of cytochromes P450.";
RL   Toxicology 82:89-104(1993).
//