Cellosaurus cell line PC (CVCL

Cross-references
Cell line name	PC
Accession	CVCL_UU13
Resource Identification Initiative	To cite this cell line use: PC (RRID:CVCL_UU13)
Comments	From: Andren-Sandberg, Ake; Karolinska Institutet; Stockholm; Sweden.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=11787853). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Unspecified (PubMed=11787853). Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Asp355Gly (c.1064A>G); Zygosity=Unspecified (PubMed=11787853). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (PubMed=11787853).
Disease	Pancreatic carcinoma (NCIt: C207229)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=11787853; DOI=10.1007/s004280100474 Moore P.S., Sipos B., Orlandini S., Sorio C., Real F.X., Lemoine N.R., Gress T.M., Bassi C., Kloppel G., Kalthoff H., Ungefroren H., Lohr J.-M., Scarpa A. Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4. Virchows Arch. 439:798-802(2001)
Cell line databases/resources	cancercelllines; CVCL_UU13
Encyclopedic resources	Wikidata; Q98128499
Polymorphism and mutation databases	IARC_TP53; 16743
Entry history
Entry creation	25-Feb-2019
Last entry update	19-Dec-2024
Version number	10