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Cellosaurus Me32a-T22/2L (CVCL_UT43)

[Text version]
Cell line name Me32a-T22/2L
Synonyms Me32a T22/2L; Me32aT22/2L
Accession CVCL_UT43
Resource Identification Initiative To cite this cell line use: Me32a-T22/2L (RRID:CVCL_UT43)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen (Note=With p.His203Gln).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRSV-T22).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:869; ATP7A; Unexplicit; 4bp deletion within exon 6; Zygosity=Unspecified (PubMed=12385784).
Disease Menkes disease (NCIt: C75486)
Menkes disease (ORDO: Orphanet_565)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_UT42 (Me32a)
Children:
CVCL_E3F0 (Me32a-T22/2L A12-H9)CVCL_E3F1 (Me32a-T22/2L C3-C1)CVCL_E3F2 (Me32a-T22/2L C3-C1 WND-16)
CVCL_E3F3 (Me32a-T22/2L C3-C1 WND-2)
Category Transformed cell line
Publications

PubMed=9813047; DOI=10.1074/jbc.273.47.31375
La Fontaine S., Firth S.D., Camakaris J., Englezou A., Theophilos M.B., Petris M.J., Howie M., Lockhart P.J., Greenough M., Brooks H., Reddel R.R., Mercer J.F.B.
Correction of the copper transport defect of Menkes patient fibroblasts by expression of the Menkes and Wilson ATPases.
J. Biol. Chem. 273:31375-31380(1998)

PubMed=12385784; DOI=10.1016/S0925-4439(02)00164-3
Lockhart P.J., La Fontaine S., Firth S.D., Greenough M., Camakaris J., Mercer J.F.B.
Correction of the copper transport defect of Menkes patient fibroblasts by expression of two forms of the sheep Wilson ATPase.
Biochim. Biophys. Acta 1588:189-194(2002)

Cross-references
Encyclopedic resources Wikidata; Q95988213
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number8