Cellosaurus cell line HK-CRISPR-mEGFP-CAP-H2 no.1 (CVCL

Cellosaurus HK-CRISPR-mEGFP-CAP-H2 no.1 (CVCL_UR46)

Cross-references
Cell line name	HK-CRISPR-mEGFP-CAP-H2 no.1
Synonyms	HK CRISPR mEGFP-CAP-H2; HK CRISPR mEGFP-NCAPH2 #1
Accession	CVCL_UR46
Resource Identification Initiative	To cite this cell line use: HK-CRISPR-mEGFP-CAP-H2 no.1 (RRID:CVCL_UR46)
Comments	Population: African American. Characteristics: Using CRISPR/Cas9D10A NCAPH2 (CAP-H2) has been endogenously tagged in both alleles at the N-terminus with mEGFP. Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; QKFJN; mEGFP (Note=Enhanced GFP). Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease	Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1922 (HeLa Kyoto)
Sex of cell	Female
Age at sampling	30Y6M
Category	Cancer cell line
Publications	PubMed=29632028; DOI=10.1083/jcb.201801048; PMCID=PMC6028534 Walther N., Hossain M.J., Politi A.Z., Koch B., Kueblbeck M., Odegard-Fougner O., Lampe M., Ellenberg J. A quantitative map of human condensins provides new insights into mitotic chromosome architecture. J. Cell Biol. 217:2309-2328(2018) PubMed=30202089; DOI=10.1038/s41586-018-0518-z; PMCID=PMC6556381 Cai Y., Hossain M.J., Heriche J.-K., Politi A.Z., Walther N., Koch B., Wachsmuth M., Nijmeijer-Winter B., Kueblbeck M., Martinic-Kavur M., Ladurner R., Alexander S., Peters J.-M., Ellenberg J. Experimental and computational framework for a dynamic protein atlas of human cell division. Nature 561:411-415(2018)
Encyclopedic resources	Wikidata; Q94210587
Entry history
Entry creation	25-Feb-2019
Last entry update	10-Apr-2025
Version number	8