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Cellosaurus K-562-luc2 (CVCL_UR39)

[Text version]
Cell line name K-562-luc2
Accession CVCL_UR39
Resource Identification Initiative To cite this cell line use: K-562-luc2 (RRID:CVCL_UR39)
Comments Population: Caucasian.
Characteristics: Stably expresses firefly luciferase under the control of the human EF1a promoter (ATCC=CCL-243-LUC2).
Doubling time: 18 +- 2 hours (ATCC=CCL-243-LUC2).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): ATCC=CCL-243-LUC2

Markers:
AmelogeninX
CSF1PO9,10
D5S81811,12,13
D7S8209,11
D13S3178
D16S53911,12
TH019.3
TPOX8,9
vWA16

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Cross-references
Cell line collections (Providers) ATCC; CCL-243-LUC2
Encyclopedic resources Wikidata; Q94333790
Entry history
Entry creation25-Feb-2019
Last entry update10-Sep-2024
Version number13