Cellosaurus cell line G-599GM (CVCL

Cellosaurus G-599GM (CVCL_UN45)

Cross-references
Cell line name	G-599GM
Accession	CVCL_UN45
Resource Identification Initiative	To cite this cell line use: G-599GM (RRID:CVCL_UN45)
Comments	Doubling time: 2.19 days (Note=In 0.5% FCS), 2.04 days (Note=In 10% FCS) (PubMed=12894509). Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg249Met (c.746G>T); ClinVar=VCV000376653; Zygosity=Unspecified (PubMed=15035290).
Disease	Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	33Y
Category	Cancer cell line
Publications	PubMed=12894509 Halatsch M.-E., Gehrke E.E., Alizadeh-Borhani F., Efferth T., Werner C., Nomikos P., Schmidt U., Buchfelder M. EGFR but not PDGFR-beta expression correlates to the antiproliferative effect of growth factor withdrawal in glioblastoma multiforme cell lines. Anticancer Res. 23:2315-2320(2003) PubMed=15035290; DOI=10.3171/jns.2004.100.3.0523 Halatsch M.-E., Gehrke E.E., Vougioukas V.I., Botefur I.C., Alizadeh-Borhani F., Efferth T., Gebhart E., Domhof S., Schmidt U., Buchfelder M. Inverse correlation of epidermal growth factor receptor messenger RNA induction and suppression of anchorage-independent growth by OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in glioblastoma multiforme cell lines. J. Neurosurg. 100:523-533(2004)
Cell line databases/resources	cancercelllines; CVCL_UN45
Encyclopedic resources	Wikidata; Q93558070
Polymorphism and mutation databases	IARC_TP53; 20246
Entry history
Entry creation	25-Feb-2019
Last entry update	19-Dec-2024
Version number	9