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Cellosaurus 518A2 (CVCL_UM77)

[Text version]
Cell line name 518A2
Synonyms 518.A2
Accession CVCL_UM77
Resource Identification Initiative To cite this cell line use: 518A2 (RRID:CVCL_UM77)
Comments Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Not specified.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_UM89 ! 518A1
CVCL_UM90 ! 518B
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=10070891; DOI=10.1038/sj.bjc.6690147; PMCID=PMC2362648
Zerp S.F., van Elsas A., Peltenburg L.T.C., Schrier P.I.
p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis.
Br. J. Cancer 79:921-926(1999)

PubMed=25502142; DOI=10.1038/ncomms6712; PMCID=PMC4428333
Muller J., Krijgsman O., Tsoi J., Robert L., Hugo W., Song C., Kong X.-J., Possik P.A., Cornelissen-Steijger P.D.M., Geukes Foppen M.H., Kemper K., Goding C.R., McDermott U., Blank C., Haanen J.B.A.G., Graeber T.G., Ribas A., Lo R.S., Peeper D.S.
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.
Nat. Commun. 5:5712.1-5712.15(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UM77
Chemistry resources ChEMBL-Cells; CHEMBL4483167
ChEMBL-Targets; CHEMBL4483222
PubChem_Cell_line; CVCL_UM77
Encyclopedic resources Wikidata; Q93307666
Gene expression databases GEO; GSM1507935
Polymorphism and mutation databases Cosmic; 1418466
IARC_TP53; 10952
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number9