Cellosaurus logo
expasy logo

Cellosaurus MM446 (CVCL_UM73)

[Text version]
Cell line name MM446
Accession CVCL_UM73
Resource Identification Initiative To cite this cell line use: MM446 (RRID:CVCL_UM73)
Comments Caution: TP53 mutation indicated incorrectly as being in position Pro315 in PubMed=10070891.
Derived from site: Metastatic; Not specified.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro316Leu (c.943_944delCCinsTT); Zygosity=Unspecified (PubMed=10070891).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=9466661; DOI=10.1002/(SICI)1097-0215(19980209)75:4<590::AID-IJC16>3.0.CO;2-D
White C.A., Thomson S.A., Cooper L.T., van Endert P.M., Tampe R., Coupar B., Qiu L., Parsons P.G., Moss D.J., Khanna R.
Constitutive transduction of peptide transporter and HLA genes restores antigen processing function and cytotoxic T cell-mediated immune recognition of human melanoma cells.
Int. J. Cancer 75:590-595(1998)

PubMed=10070891; DOI=10.1038/sj.bjc.6690147; PMCID=PMC2362648
Zerp S.F., van Elsas A., Peltenburg L.T.C., Schrier P.I.
p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis.
Br. J. Cancer 79:921-926(1999)

Cross-references
Encyclopedic resources Wikidata; Q95990244
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number7