Cellosaurus cell line Sui74 (CVCL

Cellosaurus Sui74 (CVCL_UM59)

[Text version]

Cell line name

Sui74

Accession

CVCL_UM59

Resource Identification Initiative

To cite this cell line use: Sui74 (RRID:CVCL_UM59)

Comments

Population: Japanese.
Characteristics: Established from the 74Taco16 SCID nude mouse xenograft.
Doubling time: 47.5 hours (PubMed=18691340); 34.5 hours (PubMed=35272288).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.

Sequence variations

Gene deletion; HGNC; HGNC:9884; RB1; Zygosity=Homozygous (PubMed=35272288).
Mutation; HGNC; HGNC:12637; KDM6A; Simple; p.Asn236fs*26 (c.705_706delGA) (c.702_703delAG); ClinVar=VCV002429725; Zygosity=Homozygous (PubMed=35272288).
Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Heterozygous (PubMed=18691340; PubMed=35272288).
Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.His528fs*25 (c.1582_1583delCA); Zygosity=Homozygous (PubMed=35272288).
Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=18691340).

Disease

Pancreatic adenocarcinoma (NCIt: C8294)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

72Y

Category

Cancer cell line

STR profile

Source(s): JCRB=JCRB1931

Markers:

Amelogenin	X
CSF1PO	12,13
D5S818	10,13
D7S820	11,12
D13S317	12
D16S539	13
TH01	7
TPOX	8
vWA	14,18

Publications

PubMed=18691340; DOI=10.1111/j.1349-7006.2008.00896.x; PMCID=PMC11158226
Yanagihara K., Takigahira M., Tanaka H., Arao T., Aoyagi Y., Oda T., Ochiai A., Nishio K.
Establishment and molecular profiling of a novel human pancreatic cancer panel for 5-FU.
Cancer Sci. 99:1859-1864(2008)

PubMed=35272288; DOI=10.1159/000521714
Yanagihara K., Iino Y., Yokozaki H., Kubo T., Oda T., Kubo T., Komatsu M., Sasaki H., Ichikawa H., Kuwata T., Seyama T., Ochiai A.
A comparative study of patient-derived tumor models of pancreatic ductal adenocarcinoma involving orthotopic implantation.
Pathobiology 89:222-232(2022)

Cross-references

Cell line collections (Providers)

JCRB; JCRB1931

Cell line databases/resources

cancercelllines; CVCL_UM59

Encyclopedic resources

Wikidata; Q98132877

Gene expression databases

GEO; GSM4767172

Polymorphism and mutation databases

IARC_TP53; 26976

Entry history

Entry creation

25-Feb-2019

Last entry update

19-Dec-2024

Version number