Cellosaurus cell line Sui73 (CVCL

Cellosaurus Sui73 (CVCL_UM58)

[Text][XML][JSON]

Cell line name

Sui73

Accession

CVCL_UM58

Resource Identification Initiative

To cite this cell line use: Sui73 (RRID:CVCL_UM58)

Comments

Population: Japanese.
Characteristics: Established from the 73Taco15 SCID nude mouse xenograft.
Doubling time: 23.5 hours (PubMed=18691340); 24.6 hours (PubMed=35272288).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.

Sequence variations

Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly34Glu (c.101G>A); ClinVar=VCV000017584; Zygosity=Heterozygous (PubMed=35272288).
Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000177881; Zygosity=Heterozygous (PubMed=35272288).
Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Ser32Ter (c.89_89delGA); Zygosity=Heterozygous (PubMed=35272288).
Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=18691340).

Disease

Pancreatic ductal adenocarcinoma (NCIt: C9120)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

65Y

Category

Cancer cell line

STR profile

Source(s): JCRB=JCRB1923

Markers:

Amelogenin	X
CSF1PO	10,11
D5S818	10,12
D7S820	7.3,8
D13S317	8,9
D16S539	9,10
TH01	6,7
TPOX	8,11
vWA	14,18

Publications

PubMed=18691340; DOI=10.1111/j.1349-7006.2008.00896.x; PMCID=PMC11158226
Kazuyoshi Yanagihara, Misato Takigahira, Hiromi Tanaka, Tokuzo Arao, Yasuyuki Aoyagi, Tatsuya Oda, Atsushi Ochiai, Kazuto Nishio;
Establishment and molecular profiling of a novel human pancreatic cancer panel for 5-FU.
Cancer Sci. 99:1859-1864(2008)

PubMed=35272288; DOI=10.1159/000521714
Kazuyoshi Yanagihara, Yuki Iino, Hiroshi Yokozaki, Takanori Kubo, Tatsuya Oda, Takashi Kubo, Masayuki Komatsu, Hiroki Sasaki, Hitoshi Ichikawa, Takeshi Kuwata, Toshio Seyama, Atsushi Ochiai;
A comparative study of patient-derived tumor models of pancreatic ductal adenocarcinoma involving orthotopic implantation.
Pathobiology 89:222-232(2022)

Cross-references

Cell line collections (Providers)

JCRB; JCRB1923

Encyclopedic resources

Wikidata; Q98132876

Gene expression databases

GEO; GSM4767171

Polymorphism and mutation databases

IARC_TP53; 26975

Entry history

Entry creation

25-Feb-2019

Last entry update

10-Apr-2025

Version number