Cellosaurus cell line Sui69 (CVCL

Cellosaurus Sui69 (CVCL_UM54)

[Text version]

Cell line name

Sui69

Accession

CVCL_UM54

Resource Identification Initiative

To cite this cell line use: Sui69 (RRID:CVCL_UM54)

Comments

Population: Japanese.
Characteristics: Established from the 69Taco6 SCID nude mouse xenograft.
Senescence: Has a finite life span (JCRB=JCRB1919).
Doubling time: 55.2 hours (PubMed=18691340); 35.5 hours (PubMed=35272288).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.

Sequence variations

Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=35272288).
Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Heterozygous (PubMed=18691340; PubMed=35272288).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (PubMed=18691340; PubMed=35272288).

Disease

Pancreatic ductal adenocarcinoma (NCIt: C9120)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

54Y

Category

Finite cell line

STR profile

Source(s): JCRB=JCRB1919

Markers:

Amelogenin	X,Y
CSF1PO	11,12
D5S818	10
D7S820	11
D13S317	11,12
D16S539	10,12
TH01	6,9
TPOX	8
vWA	16,18

Publications

PubMed=18691340; DOI=10.1111/j.1349-7006.2008.00896.x; PMCID=PMC11158226
Yanagihara K., Takigahira M., Tanaka H., Arao T., Aoyagi Y., Oda T., Ochiai A., Nishio K.
Establishment and molecular profiling of a novel human pancreatic cancer panel for 5-FU.
Cancer Sci. 99:1859-1864(2008)

PubMed=35272288; DOI=10.1159/000521714
Yanagihara K., Iino Y., Yokozaki H., Kubo T., Oda T., Kubo T., Komatsu M., Sasaki H., Ichikawa H., Kuwata T., Seyama T., Ochiai A.
A comparative study of patient-derived tumor models of pancreatic ductal adenocarcinoma involving orthotopic implantation.
Pathobiology 89:222-232(2022)

Cross-references

Cell line collections (Providers)

JCRB; JCRB1919

Cell line databases/resources

cancercelllines; CVCL_UM54

Encyclopedic resources

Wikidata; Q98132872

Gene expression databases

GEO; GSM4767167

Polymorphism and mutation databases

IARC_TP53; 26971

Entry history

Entry creation

25-Feb-2019

Last entry update

19-Dec-2024

Version number