ID   Sui68
AC   CVCL_UM53
DR   cancercelllines; CVCL_UM53
DR   GEO; GSM4767166
DR   IARC_TP53; 26970
DR   JCRB; JCRB1910
DR   Wikidata; Q98132870
RX   PubMed=18691340;
RX   PubMed=35272288;
CC   Population: Japanese.
CC   Characteristics: Established from the 68Taco5 SCID nude mouse xenograft.
CC   Doubling time: 43.3 hours (PubMed=18691340); 41.5 hours (PubMed=35272288).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=35272288).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (PubMed=18691340; PubMed=35272288).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Homozygous (PubMed=18691340; PubMed=35272288).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
ST   Source(s): JCRB=JCRB1910
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 10
ST   D16S539: 9
ST   D5S818: 10,12
ST   D7S820: 8,12
ST   TH01: 7,9
ST   TPOX: 8
ST   vWA: 18
DI   NCIt; C8294; Pancreatic adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   53Y
CA   Cancer cell line
DT   Created: 25-02-19; Last updated: 19-12-24; Version: 10
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RX   PubMed=18691340; DOI=10.1111/j.1349-7006.2008.00896.x; PMCID=PMC11158226;
RA   Yanagihara K., Takigahira M., Tanaka H., Arao T., Aoyagi Y., Oda T.,
RA   Ochiai A., Nishio K.;
RT   "Establishment and molecular profiling of a novel human pancreatic
RT   cancer panel for 5-FU.";
RL   Cancer Sci. 99:1859-1864(2008).
//
RX   PubMed=35272288; DOI=10.1159/000521714;
RA   Yanagihara K., Iino Y., Yokozaki H., Kubo T., Oda T., Kubo T.,
RA   Komatsu M., Sasaki H., Ichikawa H., Kuwata T., Seyama T., Ochiai A.;
RT   "A comparative study of patient-derived tumor models of pancreatic
RT   ductal adenocarcinoma involving orthotopic implantation.";
RL   Pathobiology 89:222-232(2022).
//