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Cellosaurus RC-17 SNCA+/- clone L5-4 (CVCL_UL63)

[Text version]
Cell line name RC-17 SNCA+/- clone L5-4
Accession CVCL_UL63
Resource Identification Initiative To cite this cell line use: RC-17 SNCA+/- clone L5-4 (RRID:CVCL_UL63)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11138; SNCA (Note=1 of 2 alleles).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_L206 (RC-17)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=30472757; DOI=10.1111/ejn.14286; PMCID=PMC6492083
Chen Y.-X., Dolt K.S., Kriek M., Baker T., Downey P., Drummond N.J., Canham M.A., Natalwala A., Rosser S., Kunath T.
Engineering synucleinopathy-resistant human dopaminergic neurons by CRISPR-mediated deletion of the SNCA gene.
Eur. J. Neurosci. 49:510-524(2019)

Cross-references
Encyclopedic resources Wikidata; Q98128852
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number6