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HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity.
Hum. Mol. Genet. 24:3257-3271(2015)

PubMed=28526555; DOI=10.1016/j.stem.2017.04.002; PMCID=PMC6659720
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Modeling psychomotor retardation using iPSCs from MCT8-deficient patients indicates a prominent role for the blood-brain barrier.
Cell Stem Cell 20:831-843.e5(2017)