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Cellosaurus NLF-TrkB, clone #6 (CVCL_UJ93)

[Text version]
Cell line name NLF-TrkB, clone #6
Synonyms NLF-TrkB, NTA#6
Accession CVCL_UJ93
Resource Identification Initiative To cite this cell line use: NLF-TrkB, clone #6 (RRID:CVCL_UJ93)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:8032; NTRK2.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Arg524Met (c.1571G>T); Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E217 (NLF)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
Publications

PubMed=26797418; DOI=10.1016/j.canlet.2016.01.018; PMCID=PMC4792275
Iyer R., Wehrmann L., Golden R.L., Naraparaju K., Croucher J.L., MacFarland S.P., Guan P., Kolla V., Wei G., Cam N., Li G., Hornby Z., Brodeur G.M.
Entrectinib is a potent inhibitor of Trk-driven neuroblastomas in a xenograft mouse model.
Cancer Lett. 372:179-186(2016)

Cross-references
Cell line collections (Providers) Kerafast; ECP010
Encyclopedic resources Wikidata; Q98127940
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number8