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Cellosaurus A549 ATGL-KO (CVCL_UJ32)

[Text version]
Cell line name A549 ATGL-KO
Accession CVCL_UJ32
Resource Identification Initiative To cite this cell line use: A549 ATGL-KO (RRID:CVCL_UJ32)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:30802; PNPLA2.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=29457907; DOI=10.1021/acs.jproteome.7b00782
Tomin T., Fritz K., Gindlhuber J., Waldherr L., Pucher B., Thallinger G.G., Nomura D.K., Schittmayer M., Birner-Gruenberger R.
Deletion of adipose triglyceride lipase links triacylglycerol accumulation to a more-aggressive phenotype in A549 lung carcinoma cells.
J. Proteome Res. 17:1415-1425(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UJ32
Encyclopedic resources Wikidata; Q93311893
Proteomic databases PRIDE; PXD007223
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number8