Cellosaurus logo
expasy logo

Cellosaurus POT1a F/F POT1b F/F (#20431-5) (CVCL_UJ01)

[Text version]
Cell line name POT1a F/F POT1b F/F (#20431-5)
Synonyms POT1a F/F POT1b F/F(#20431-5)
Accession CVCL_UJ01
Resource Identification Initiative To cite this cell line use: POT1a F/F POT1b F/F (#20431-5) (RRID:CVCL_UJ01)
Comments Characteristics: Embryonic fibroblasts that have loxP sites on both sides of the 3rd coding exon of mouse Pot1a and Pot1b genes. Pot1a anb Pot1b knockout can be effected by transduction of Cre recombinase into the cell line (ATCC=CRL-3323).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: 129P2/Ola x C57BL/6J.
Sex of cell Sex unspecified
Age at sampling 13-14FD
Category Transformed cell line
Publications

PubMed=16839877; DOI=10.1016/j.cell.2006.04.044
Hockemeyer D., Daniels J.-P., Takai H., de Lange T.
Recent expansion of the telomeric complex in rodents: two distinct POT1 proteins protect mouse telomeres.
Cell 126:63-77(2006)

Cross-references
Cell line collections (Providers) ATCC; CRL-3323
Encyclopedic resources Wikidata; Q98128656
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number6