DR   cancercelllines; CVCL_UI87
DR   Wikidata; Q98128407
RX   PubMed=21372221;
RX   PubMed=30485824;
CC   Problematic cell line: Possibly misclassified. Parent cell line (OVCAR-5) was originally thought to be a high grade ovarian serous adenocarcinoma but suspected to have a upper gastrointestinal origin.
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
CC   Omics: Genome sequenced.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
ST   Source(s): PubMed=30485824
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 10,13
ST   D16S539: 11
ST   D21S11: 31
ST   D5S818: 11,13
ST   D7S820: 10
ST   TH01: 7,9.3
ST   TPOX: 8,11
ST   vWA: 16
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1628 ! OVCAR-5
SX   Female
AG   67Y
CA   Cancer cell line
DT   Created: 25-02-19; Last updated: 05-10-23; Version: 9
RX   PubMed=21372221; DOI=10.1158/1078-0432.CCR-10-2289;
RA   Santiskulvong C., Konecny G.E., Fekete M., Chen K.-Y.M., Karam A.,
RA   Mulholland D., Eng C., Wu H., Song M., Dorigo O.;
RT   "Dual targeting of phosphoinositide 3-kinase and mammalian target of
RT   rapamycin using NVP-BEZ235 as a novel therapeutic approach in human
RT   ovarian carcinoma.";
RL   Clin. Cancer Res. 17:2373-2384(2011).
RX   PubMed=30485824; DOI=10.1016/j.celrep.2018.10.096;
RA   Papp E., Hallberg D., Konecny G.E., Bruhm D.C., Adleff V., Noe M.,
RA   Kagiampakis I., Palsgrove D., Conklin D., Kinose Y., White J.R.,
RA   Press M.F., Drapkin R.I., Easwaran H., Baylin S.B., Slamon D.J.,
RA   Velculescu V.E., Scharpf R.B.;
RT   "Integrated genomic, epigenomic, and expression analyses of ovarian
RT   cancer cell lines.";
RL   Cell Rep. 25:2617-2633(2018).