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Cellosaurus hTERT SC ipn97.4 (CVCL_UI66)

[Text version]
Cell line name hTERT SC ipn97.4
Synonyms ipn97.4
Accession CVCL_UI66
Resource Identification Initiative To cite this cell line use: hTERT SC ipn97.4 (RRID:CVCL_UI66)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=MGI; MGI:88357; Cdk4.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Peripheral nervous system, nerve; UBERON=UBERON_0001021.
Cell type: Schwann cell; CL=CL_0002573.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Telomerase immortalized cell line
Publications

PubMed=27617404; DOI=10.1038/labinvest.2016.88
Li H., Chang L.-J., Neubauer D.R., Muir D.F. 4th, Wallace M.R.
Immortalization of human normal and NF1 neurofibroma Schwann cells.
Lab. Invest. 96:1105-1115(2016)

PubMed=29055717; DOI=10.1016/j.expneurol.2017.10.012; PMCID=PMC6863155
Kraniak J.M., Chalasani A., Wallace M.R., Mattingly R.R.
Development of 3D culture models of plexiform neurofibroma and initial application for phenotypic characterization and drug screening.
Exp. Neurol. 299:289-298(2018)

PubMed=29893754; DOI=10.1038/sdata.2018.106; PMCID=PMC5996849
Ferrer M., Gosline S.J.C., Stathis M., Zhang X.-H., Guo X.-D., Guha R., Ryman D.A., Wallace M.R., Kasch-Semenza L., Hao H.-P., Ingersoll R.G., Mohr D., Thomas C.J., Verma S., Guinney J.H., Blakeley J.O.
Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived Schwann cells.
Sci. Data 5:180106.1-180106.12(2018)

Cross-references
Cell line collections (Providers) ABM; T0196
Encyclopedic resources Wikidata; Q94305889
Entry history
Entry creation25-Feb-2019
Last entry update10-Apr-2025
Version number9