Cellosaurus cell line SU/SR (CVCL

Cross-references
Cell line name	SU/SR
Accession	CVCL_UI51
Resource Identification Initiative	To cite this cell line use: SU/SR (RRID:CVCL_UI51)
Comments	Population: Japanese. Selected for resistance to: ChEBI; CHEBI_45783; Imatinib (Gleevec; STI571). Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations	Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=18783828). Mutation; HGNC; HGNC:76; ABL1; Simple; p.Thr315Ile (c.944C>T) (c.1001C>T); ClinVar=VCV000012624; Zygosity=Unspecified (PubMed=18783828).
Disease	Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C114819) B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_UI50 (SU-Ph2)
Sex of cell	Female
Age at sampling	50Y
Category	Cancer cell line
Publications	PubMed=18783828; DOI=10.1016/j.leukres.2008.07.023 Hirase C., Maeda Y., Takai S., Kanamaru A. Hypersensitivity of Ph-positive lymphoid cell lines to rapamycin: possible clinical application of mTOR inhibitor. Leuk. Res. 33:450-459(2009)
Cell line databases/resources	cancercelllines; CVCL_UI51
Encyclopedic resources	Wikidata; Q98132865
Entry history
Entry creation	25-Feb-2019
Last entry update	19-Dec-2024
Version number	11