ID   U-HO1-PTPN1
AC   CVCL_UI40
DR   Cell_Model_Passport; SIDM01913
DR   Wikidata; Q98133718
RX   CelloPub=CLPUB00457;
RX   PubMed=21144060;
CC   Sequence variation: Mutation; HGNC; 9642; PTPN1; Unexplicit; Ex2-8del; Zygosity=Unspecified (CelloPub=CLPUB00457).
CC   Transfected with: HGNC; 9642; PTPN1.
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C9357; Hodgkin lymphoma
DI   ORDO; Orphanet_98293; Hodgkin lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2220 ! U-HO1
SX   Male
AG   23Y
CA   Cancer cell line
DT   Created: 25-02-19; Last updated: 29-06-23; Version: 7
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RX   CelloPub=CLPUB00457;
RA   Wegener S., Mader A., Melzner I., Bruderlein S., Moller P.;
RT   "Lack of PTPN1 (PTP1B) in U-HO1, a new Hodgkin-derived cell line,
RT   protects cells from apoptosis.";
RL   Haematologica 92 Suppl. 5:39-39(2007).
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RX   PubMed=21144060; DOI=10.1186/1471-2121-11-99;
RA   Knecht H., Bruderlein S., Wegener S., Lichtensztejn D.,
RA   Lichtensztejn Z., Lemieux B., Moller P., Mai S.;
RT   "3D nuclear organization of telomeres in the Hodgkin cell lines U-HO1
RT   and U-HO1-PTPN1: PTPN1 expression prevents the formation of very short
RT   telomeres including 't-stumps'.";
RL   BMC Cell Biol. 11:99.1-99.10(2010).
//