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Cellosaurus NPC43 (CVCL_UH64)

[Text version]
Cell line name NPC43
Accession CVCL_UH64
Resource Identification Initiative To cite this cell line use: NPC43 (RRID:CVCL_UH64)
Comments Population: Chinese.
Virology: Contains 15-20 copies per cell of EBV genome.
Doubling time: 8 days (Note=At 22th passage), 4 days (Note=At 90th passage), 2.5 days (Note=At 200th passage) (PubMed=30405107).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Pharynx, nasopharynx; UBERON=UBERON_0001728.
Sequence variations
Disease Nasopharyngeal carcinoma (NCIt: C3871)
Nasopharyngeal carcinoma (ORDO: Orphanet_150)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): PubMed=30405107

Markers:
AmelogeninX
CSF1PO13
D3S135818
D5S81811
D7S82012,13
D8S117911
D13S31712
D16S53910
D18S5113,15
D21S1132
FGA22
Penta D8
TH017
TPOX8
vWA14,16

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Publications

PubMed=30405107; DOI=10.1038/s41467-018-06889-5; PMCID=PMC6220246
Lin W.-T., Yip Y.-L., Jia L., Deng W., Zheng H., Dai W., Ko J.M.-Y., Lo K.-W., Chung G.T.-Y., Yip K.Y.-L., Lee S.-D., Kwan J.S.-H., Zhang J., Liu T.-F., Chan J.Y.-W., Kwong D.L.-W., Lee V.H.-F., Nicholls J.M., Busson P., Liu X.-F., Chiang A.K.-S., Hui K.-F., Kwok H., Cheung S.-T., Cheung Y.-C., Chan C.-K., Li B., Cheung A.L.-M., Hau P.-M., Zhou Y., Tsang C.-M., Middeldorp J.M., Chen H.-L., Lung M.L., Tsao S.-W.
Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma.
Nat. Commun. 9:4663.1-4663.17(2018)

DOI=10.1016/B978-0-12-814936-2.00005-5
Yip Y.-L., Lin W.-T., Deng W., Tsang C.-M., Tsao S.-W.
Establishment of nasopharyngeal carcinoma cell lines, patient-derived xenografts, and immortalized nasopharyngeal epithelial cell lines for nasopharyngeal carcinoma and Epstein-Barr virus infection studies.
(In book chapter) Nasopharyngeal carcinoma. From etiology to clinical practice; Lee A.W.-M., Lung M.L., Ng W.T. (eds.); pp.85-107; Academic Press; New York; USA (2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UH64
Cell_Model_Passport; SIDM01992
Encyclopedic resources Wikidata; Q98128017
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number12