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Cellosaurus HEK293 CYP2D6*10 (CVCL_UH09)

[Text version]
Cell line name HEK293 CYP2D6*10
Synonyms CYP2D6*10 (P34S/S486T) Expressing HEK293 Cell Line
Accession CVCL_UH09
Resource Identification Initiative To cite this cell line use: HEK293 CYP2D6*10 (RRID:CVCL_UH09)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:2625; CYP2D6 (Note=With p.Pro34Ser and p.Ser486Thr).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Miscellaneous: Cell line has been lost. Attempt to re-clone it are underway.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=28603633; DOI=10.1002/prp2.314; PMCID=PMC5464343
Peterson A., Xia Z.-P., Chen G., Lazarus P.
In vitro metabolism of exemestane by hepatic cytochrome P450s: impact of nonsynonymous polymorphisms on formation of the active metabolite 17beta-dihydroexemestane.
Pharmacol. Res. Perspect. 5:e00314.1-e00314.16(2017)

Cross-references
Encyclopedic resources Wikidata; Q94093000
Entry history
Entry creation13-Nov-2018
Last entry update19-Dec-2024
Version number8