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Cellosaurus HEK293 CYP2C8*3-V5 (CVCL_UG92)

[Text version]
Cell line name HEK293 CYP2C8*3-V5
Synonyms CYP2C8*3 (R139K/K399R - V5 tag) Expressing HEK293 Cell Line
Accession CVCL_UG92
Resource Identification Initiative To cite this cell line use: HEK293 CYP2C8*3-V5 (RRID:CVCL_UG92)
Comments Characteristics: Expresses CYP2C8*3 with a C-terminal V5 tag.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:2622; CYP2C8 (Note=With p.Arg139Lys and p.Lys399Arg).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=28603633; DOI=10.1002/prp2.314; PMCID=PMC5464343
Peterson A., Xia Z.-P., Chen G., Lazarus P.
In vitro metabolism of exemestane by hepatic cytochrome P450s: impact of nonsynonymous polymorphisms on formation of the active metabolite 17beta-dihydroexemestane.
Pharmacol. Res. Perspect. 5:e00314.1-e00314.16(2017)

Cross-references
Cell line collections (Providers) Kerafast; EWU015 - Discontinued
Encyclopedic resources Wikidata; Q94092964
Entry history
Entry creation13-Nov-2018
Last entry update19-Dec-2024
Version number7