Cellosaurus cell line ICGi006-B (CVCL

Cellosaurus ICGi006-B (CVCL_UF68)

Cross-references
Cell line name	ICGi006-B
Synonyms	m3SMA20
Accession	CVCL_UF68
Resource Identification Initiative	To cite this cell line use: ICGi006-B (RRID:CVCL_UF68)
Comments	From: The Federal Research Center Institute of Cytology and Genetics; Novosibirsk; Russia. Population: Caucasian. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Gene amplification; HGNC; HGNC:11118; SMN2; Triplication; Zygosity=Unspecified (PubMed=30660867). Gene deletion; HGNC; HGNC:11117; SMN1; Zygosity=Homozygous (PubMed=30660867).
Disease	Spinal muscular atrophy type 2 (NCIt: C156310) Proximal spinal muscular atrophy type 2 (ORDO: Orphanet_83418)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_UF67 ! ICGi006-A
Sex of cell	Male
Age at sampling	34Y
Category	Induced pluripotent stem cell
Publications	PubMed=30660867; DOI=10.1016/j.scr.2018.101376 Valetdinova K.R., Maretina M.A., Kuranova M.L., Grigor'eva E.V., Minina J.M., Kizilova E.A., Kiselev A.V., Medvedev S.P., Baranov V.S., Zakian S.M. Generation of two spinal muscular atrophy (SMA) type I patient-derived induced pluripotent stem cell (iPSC) lines and two SMA type II patient-derived iPSC lines. Stem Cell Res. 34:101376-101376(2019)
Cell line databases/resources	hPSCreg; ICGi006-B
Biological sample resources	BioSamples; SAMEA5131666
Encyclopedic resources	Wikidata; Q94313415
Entry history
Entry creation	13-Nov-2018
Last entry update	19-Dec-2024
Version number	11