Cellosaurus cell line ICGi005-A (CVCL

Cellosaurus ICGi005-A (CVCL_UF65)

Cross-references
Cell line name	ICGi005-A
Synonyms	iSMA40
Accession	CVCL_UF65
Resource Identification Initiative	To cite this cell line use: ICGi005-A (RRID:CVCL_UF65)
Comments	From: The Federal Research Center Institute of Cytology and Genetics; Novosibirsk; Russia. Population: Caucasian. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Gene deletion; HGNC; HGNC:11117; SMN1; Zygosity=Homozygous (PubMed=30660867).
Disease	Werdnig-Hoffmann disease (NCIt: C98670) Proximal spinal muscular atrophy type 1 (ORDO: Orphanet_83330)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_UF66 ! ICGi005-B
Sex of cell	Female
Age at sampling	10Y
Category	Induced pluripotent stem cell
Publications	CLPUB00461 Grigor'eva E.V., Valetdinova K.R., Ustyantseva E.I., Shevchenko A.I., Medvedev S.P., Mazurok N.A., Maretina M.A., Kuranova M.L., Kiselev A.V., Baranov V.S., Zakian S.M. Neural differentiation of patient-specific induced pluripotent stem cells from patients with a hereditary form of spinal muscular atrophy. Geny i Kletki 11:2.70-2.79(2016) PubMed=30660867; DOI=10.1016/j.scr.2018.101376 Valetdinova K.R., Maretina M.A., Kuranova M.L., Grigor'eva E.V., Minina J.M., Kizilova E.A., Kiselev A.V., Medvedev S.P., Baranov V.S., Zakian S.M. Generation of two spinal muscular atrophy (SMA) type I patient-derived induced pluripotent stem cell (iPSC) lines and two SMA type II patient-derived iPSC lines. Stem Cell Res. 34:101376-101376(2019)
Cell line databases/resources	hPSCreg; ICGi005-A
Biological sample resources	BioSamples; SAMEA5100024
Encyclopedic resources	Wikidata; Q94313406
Entry history
Entry creation	13-Nov-2018
Last entry update	19-Dec-2024
Version number	11