ID   NP-2/CD4/iGFP
AC   CVCL_UF00
DR   cancercelllines; CVCL_UF00
DR   Wikidata; Q98128011
RX   PubMed=22178016;
CC   Population: Japanese.
CC   Characteristics: GFP-inducible indicator cell line produced by transfection of the pHIV-LTR-GFP-NLS plasmid, containing HIV-1 long terminal repeat (LTR), eGFP, the nuclear localization signal (NLS) of HIV-1 Rev and pac.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met237Ile (c.711G>T); ClinVar=VCV000634770; Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1678; CD4.
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Brain, left frontal lobe; UBERON=UBERON_0002811.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_UE99 ! NP-2/iGFP
SX   Male
AG   63Y
CA   Cancer cell line
DT   Created: 13-11-18; Last updated: 19-12-24; Version: 9
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RX   PubMed=22178016; DOI=10.1016/j.micinf.2011.11.005;
RA   Hoque S.A., Ohtsuki T., Tatsumi M., Shimizu N., Islam S.,
RA   Jinno-Oue A., Hoshino H.;
RT   "Lack of the trans-receptor mechanism of HIV-1 infection: CD4- and
RT   coreceptor-independent incorporation of HIV-1-resistant cells into
RT   syncytia induced by HIV-1.";
RL   Microbes Infect. 14:357-368(2012).
//