Cellosaurus cell line OCI-AML-20 (CVCL

Cellosaurus OCI-AML-20 (CVCL_UE33)

[Text version]

Cell line name

OCI-AML-20

Synonyms

OCI-AML20; Ontario Cancer Institute-Acute Myeloid Leukemia-20

Accession

CVCL_UE33

Resource Identification Initiative

To cite this cell line use: OCI-AML-20 (RRID:CVCL_UE33)

Comments

Doubling time: 57 hours (PubMed=30352278).
Karyotypic information: Monosomy of chromosome 7 (PubMed=30352278).
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.

Sequence variations

Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (PubMed=30352278).

Disease

Acute myeloid leukemia with inv(3) (q21.3;q26.2) or t(3;3) (q21.3;q26.2) GATA2, MECOM (NCIt: C82426)
Acute myeloid leukemia with inv3(q21;q26.2) or t(3;3)(q21;q26.2) (ORDO: Orphanet_402020)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

34Y

Category

Cancer cell line

STR profile

Source(s): PubMed=30352278

Markers:

Amelogenin	X,Y
CSF1PO	11,12
D5S818	11,12
D7S820	8
D13S317	8,11
D16S539	8,12
D21S11	30
TH01	6,9.3
TPOX	10,11
vWA	19,20

Publications

PubMed=30352278; DOI=10.1016/j.exphem.2018.10.006
Luciani G.M., Xie L.-H., Dilworth D., Tierens A., Moskovitz Y., Murison A., Szewczyk M.M., Mitchell A., Lupien M., Shlush L.I., Dick J.E., Arrowsmith C.H., Barsyte-Lovejoy D., Minden M.D.
Characterization of inv(3) cell line OCI-AML-20 with stroma-dependent CD34 expression.
Exp. Hematol. 69:27-36(2019)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_UE33

Encyclopedic resources

Wikidata; Q98128326

Gene expression databases

GEO; GSE120834

Entry history

Entry creation

13-Nov-2018

Last entry update

19-Dec-2024

Version number