ID   OVPA8
AC   CVCL_UC75
SY   OVPA-8
DR   cancercelllines; CVCL_UC75
DR   DSMZ; ACC-871
DR   DSMZCellDive; ACC-871
DR   ECACC; 19062601
DR   Wikidata; Q98128408
RX   PubMed=30018258;
CC   Population: Caucasian.
CC   Doubling time: ~44 hours (PubMed=30018258); 50-60 hours (DSMZ=ACC-871); 40-44 hours (ECACC=19062601).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1101; BRCA2; Zygosity=Heterozygous (PubMed=30018258).
CC   Sequence variation: Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Val1234Glnfs*8 (c.3695_3699GTAAA[1]) (c.3700_3704delGTAAA) (3819del5) (3819_3823delGTAAA); ClinVar=VCV000037542; Zygosity=Homozygous (PubMed=30018258).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Homozygous (PubMed=30018258).
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
ST   Source(s): DSMZ=ACC-871; ECACC=19062601; PubMed=30018258
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D10S1248: 14,15
ST   D12S391: 21
ST   D13S317: 11
ST   D16S539: 12,14
ST   D18S51: 12
ST   D19S433: 13,15
ST   D1S1656: 15
ST   D21S11: 29,30
ST   D22S1045: 15
ST   D2S1338: 21,25
ST   D2S441: 14
ST   D3S1358: 15
ST   D5S818: 9,13
ST   D7S820: 8,9
ST   D8S1179: 11,14 (DSMZ=ACC-871; PubMed=30018258)
ST   D8S1179: 14 (ECACC=19062601)
ST   FGA: 22,25
ST   Penta D: 13
ST   Penta E: 5
ST   TH01: 8
ST   TPOX: 9,11
ST   vWA: 14
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   47Y
CA   Cancer cell line
DT   Created: 13-11-18; Last updated: 19-12-24; Version: 12
//
RX   PubMed=30018258; DOI=10.3390/ijms19072080; PMCID=PMC6073376;
RA   Tudrej P., Olbryt M., Zembala-Nozynska E., Kujawa K.A., Cortez A.J.,
RA   Fiszer-Kierzkowska A., Piglowski W., Nikiel B., Glowala-Kosinska M.,
RA   Bartkowska-Chrobok A., Smagur A., Fidyk W., Lisowska K.M.;
RT   "Establishment and characterization of the novel high-grade serous
RT   ovarian cancer cell line OVPA8.";
RL   Int. J. Mol. Sci. 19:2080.1-2080.26(2018).
//