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Cellosaurus LM-MEL-62 (CVCL_UC60)

[Text version]
Cell line name LM-MEL-62
Synonyms LM-Mel-62; Ludwig Melbourne-MELanoma-62
Accession CVCL_UC60
Resource Identification Initiative To cite this cell line use: LM-MEL-62 (RRID:CVCL_UC60)
Comments Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Doubling time: ~38 hours (ATCC=CRL-3339).
Omics: miRNA expression profiling.
Omics: Transcriptome analysis by microarray.
Miscellaneous: STR profile from personal communication of Cardwell, Tracy.
Derived from site: Metastatic; Right axillary lymph node; UBERON=UBERON_0001097.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Gly469Glu (c.1406G>A) (p.Gly509Glu, c.1526G>A); ClinVar=VCV000013974; Zygosity=Unspecified (PubMed=23527996).
HLA typing Source: PubMed=23527996
Class I
HLA-AA*02:01,31:01
HLA-BB*07:02,60
HLA-CC*03:04,07:02
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3339; Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO10
D5S81810,12
D7S82011
D13S31710,13
D16S53910
D21S1129,30
TH017
TPOX11
vWA15

Run an STR similarity search on this cell line
Publications

PubMed=19221743; DOI=10.1007/s00262-009-0672-0; PMCID=PMC11029848
Gedye C., Quirk J., Browning J., Svobodova S., John T., Sluka P., Dunbar P.R., Corbeil D., Cebon J.S., Davis I.D.
Cancer/testis antigens can be immunological targets in clonogenic CD133+ melanoma cells.
Cancer Immunol. Immunother. 58:1635-1646(2009)

PubMed=22102544; DOI=10.1002/stem.786
Anaka M., Freyer C., Gedye C., Caballero O.L., Davis I.D., Behren A., Cebon J.S.
Stem cell media culture of melanoma results in the induction of a nonrepresentative neural expression profile.
Stem Cells 30:336-343(2012)

PubMed=23527996; DOI=10.1111/pcmr.12097
Behren A., Anaka M., Lo P.-H., Vella L.J., Davis I.D., Catimel J., Cardwell T., Gedye C., Hudson C., Stan R., Cebon J.S.
The Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Pigment Cell Melanoma Res. 26:597-600(2013)

PubMed=27852308; DOI=10.1186/s12943-016-0554-y; PMCID=PMC5112703
Andrews M.C., Cursons J., Hurley D.G., Anaka M., Cebon J.S., Behren A., Crampin E.J.
Systems analysis identifies miR-29b regulation of invasiveness in melanoma.
Mol. Cancer 15:72.1-72.20(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-3339
Cell line databases/resources cancercelllines; CVCL_UC60
Encyclopedic resources Wikidata; Q95982557
Gene expression databases ArrayExpress; E-MTAB-1496
GEO; GSM2371785
Entry history
Entry creation13-Nov-2018
Last entry update19-Dec-2024
Version number10