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Cellosaurus LM-MEL-53 (CVCL_UC56)

[Text version]
Cell line name LM-MEL-53
Synonyms LM-Mel-53; Ludwig Melbourne-MELanoma-53
Accession CVCL_UC56
Resource Identification Initiative To cite this cell line use: LM-MEL-53 (RRID:CVCL_UC56)
Comments Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Doubling time: ~40 hours (ATCC=CRL-3337).
Omics: miRNA expression profiling.
Omics: Transcriptome analysis by microarray.
Miscellaneous: STR profile from personal communication of Cardwell T., Olivia Newton-John Cancer Research Institute.
Derived from site: Metastatic; Soft tissue; UBERON=UBERON_0034929.
HLA typing Source: PubMed=23527996
Class I
HLA-AA*02:01
HLA-BB*60,44:02
HLA-CC*03:04,05:01
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_UC49 ! LM-MEL-44
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): ATCC; Direct_author_submission

Markers:
AmelogeninX
CSF1PO11,14
D5S81811,12
D7S82011,12
D13S3179,13
D16S53912
D21S1128,30,32,33
TH016,8
TPOX11
vWA16,19

Run an STR similarity search on this cell line
Publications

PubMed=18413770; DOI=10.1158/0008-5472.CAN-07-5664
Ebert L.M., Tan B.S., Browning J., Svobodova S., Russell S.E., Kirkpatrick N.C., Gedye C., Moss D.J., Ng S.P., MacGregor D.P., Davis I.D., Cebon J.S., Chen W.-S.
The regulatory T cell-associated transcription factor FoxP3 is expressed by tumor cells.
Cancer Res. 68:3001-3009(2008)

PubMed=23527996; DOI=10.1111/pcmr.12097
Behren A., Anaka M., Lo P.-H., Vella L.J., Davis I.D., Catimel J., Cardwell T., Gedye C., Hudson C., Stan R., Cebon J.S.
The Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Pigment Cell Melanoma Res. 26:597-600(2013)

PubMed=27852308; DOI=10.1186/s12943-016-0554-y
Andrews M.C., Cursons J., Hurley D.G., Anaka M., Cebon J.S., Behren A., Crampin E.J.
Systems analysis identifies miR-29b regulation of invasiveness in melanoma.
Mol. Cancer 15:72.1-72.20(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-3337
Encyclopedic resources Wikidata; Q95982547
Gene expression databases ArrayExpress; E-MTAB-1496
GEO; GSM2371781
Entry history
Entry creation13-Nov-2018
Last entry update29-Jun-2023
Version number4