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Cellosaurus LM-MEL-45 (CVCL_UC50)

[Text version]
Cell line name LM-MEL-45
Synonyms LM-Mel-45; Ludwig Melbourne-MELanoma-45
Accession CVCL_UC50
Resource Identification Initiative To cite this cell line use: LM-MEL-45 (RRID:CVCL_UC50)
Comments Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Doubling time: ~40 hours (ATCC=CRL-3336).
Omics: miRNA expression profiling.
Omics: Transcriptome analysis by microarray.
Miscellaneous: STR profile from personal communication of Cardwell T., Olivia Newton-John Cancer Research Institute.
Derived from site: Metastatic; Brain, right occipital lobe; UBERON=UBERON_0002807.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23527996).
HLA typing Source: PubMed=23527996
Class I
HLA-AA*02:01,03:01
HLA-BB*07:02,57:01
HLA-CC*06:02,07:02
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_UC44 ! LM-MEL-38a
Sex of cell Female
Age at sampling 33Y
Category Cancer cell line
STR profile Source(s): ATCC; Direct_author_submission

Markers:
AmelogeninX
CSF1PO11
D5S81811
D7S82010,13
D13S31711,14
D16S53911,13
D21S1132
TH019.3
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=23527996; DOI=10.1111/pcmr.12097
Behren A., Anaka M., Lo P.-H., Vella L.J., Davis I.D., Catimel J., Cardwell T., Gedye C., Hudson C., Stan R., Cebon J.S.
The Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Pigment Cell Melanoma Res. 26:597-600(2013)

PubMed=27852308; DOI=10.1186/s12943-016-0554-y
Andrews M.C., Cursons J., Hurley D.G., Anaka M., Cebon J.S., Behren A., Crampin E.J.
Systems analysis identifies miR-29b regulation of invasiveness in melanoma.
Mol. Cancer 15:72.1-72.20(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-3336
Cell line databases/resources cancercelllines; CVCL_UC50
Encyclopedic resources Wikidata; Q95982538
Gene expression databases ArrayExpress; E-MTAB-1496
GEO; GSM2371775
Entry history
Entry creation13-Nov-2018
Last entry update05-Oct-2023
Version number7