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Cellosaurus LM-MEL-24 (CVCL_UC32)

[Text version]
Cell line name LM-MEL-24
Synonyms LM-Mel-24; Ludwig Melbourne-MELanoma-24
Accession CVCL_UC32
Resource Identification Initiative To cite this cell line use: LM-MEL-24 (RRID:CVCL_UC32)
Comments Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Omics: miRNA expression profiling.
Omics: Transcriptome analysis by microarray.
Miscellaneous: Metastatic site and STR profile from personal communication of Cardwell T., Olivia Newton-John Cancer Research Institute.
Derived from site: Metastatic; Brain, left parietal lobe; UBERON=UBERON_0002802.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Lys (c.1798_1799delGTinsAA); ClinVar=VCV000375941; Zygosity=Unspecified (PubMed=23527996).
HLA typing Source: PubMed=23527996
Class I
HLA-AA*01,02
HLA-BB*08,44
HLA-CC*05,07
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 38Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO11
D5S81812
D7S82012
D13S3179
D16S53911,12
D21S1130,30.2
TH018
TPOX10,12
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=18413770; DOI=10.1158/0008-5472.CAN-07-5664
Ebert L.M., Tan B.S., Browning J., Svobodova S., Russell S.E., Kirkpatrick N.C., Gedye C., Moss D.J., Ng S.P., MacGregor D.P., Davis I.D., Cebon J.S., Chen W.-S.
The regulatory T cell-associated transcription factor FoxP3 is expressed by tumor cells.
Cancer Res. 68:3001-3009(2008)

PubMed=23527996; DOI=10.1111/pcmr.12097
Behren A., Anaka M., Lo P.-H., Vella L.J., Davis I.D., Catimel J., Cardwell T., Gedye C., Hudson C., Stan R., Cebon J.S.
The Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Pigment Cell Melanoma Res. 26:597-600(2013)

PubMed=27852308; DOI=10.1186/s12943-016-0554-y
Andrews M.C., Cursons J., Hurley D.G., Anaka M., Cebon J.S., Behren A., Crampin E.J.
Systems analysis identifies miR-29b regulation of invasiveness in melanoma.
Mol. Cancer 15:72.1-72.20(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UC32
Encyclopedic resources Wikidata; Q95982508
Gene expression databases ArrayExpress; E-MTAB-1496
GEO; GSM2371757
Entry history
Entry creation13-Nov-2018
Last entry update05-Oct-2023
Version number8