ID   LM-MEL-3
AC   CVCL_UC18
SY   LM-Mel-3; Ludwig Melbourne-MELanoma-3
DR   ArrayExpress; E-MTAB-1496
DR   cancercelllines; CVCL_UC18
DR   GEO; GSM2371743
DR   Wikidata; Q95982518
RX   PubMed=18957296;
RX   PubMed=23527996;
RX   PubMed=27852308;
CC   Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
CC   HLA typing: A*01:01,24:02; B*07:02,08:01; C*07:01,07:02 (PubMed=23527996).
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23527996).
CC   Sequence variation: Mutation; HGNC; 6840; MAP2K1; Simple; p.Pro124Leu (c.371C>T); ClinVar=VCV000040744; Zygosity=Heterozygous (Direct_author_submission).
CC   Omics: miRNA expression profiling.
CC   Omics: Transcriptome analysis by microarray.
CC   Miscellaneous: MAP2K1 mutation, metastatic site and STR profile from personal communication of Cardwell T., Olivia Newton-John Cancer Research Institute.
CC   Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
ST   Source(s): Direct_author_submission
ST   Amelogenin: X
ST   CSF1PO: 13
ST   D13S317: 11,12
ST   D16S539: 13,14
ST   D21S11: 29
ST   D5S818: 12
ST   D7S820: 10,12
ST   TH01: 7,9.3
ST   TPOX: 8,11
ST   vWA: 17
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   54Y
CA   Cancer cell line
DT   Created: 13-11-18; Last updated: 05-10-23; Version: 10
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RX   PubMed=18957296; DOI=10.1016/j.jim.2008.09.023;
RA   Dimopoulos N., Jackson H.M., Ebert L., Guillaume P., Luescher I.F.,
RA   Ritter G., Chen W.-S.;
RT   "Combining MHC tetramer and intracellular cytokine staining for CD8(+)
RT   T cells to reveal antigenic epitopes naturally presented on tumor
RT   cells.";
RL   J. Immunol. Methods 340:90-94(2009).
//
RX   PubMed=23527996; DOI=10.1111/pcmr.12097;
RA   Behren A., Anaka M., Lo P.-H., Vella L.J., Davis I.D., Catimel J.,
RA   Cardwell T., Gedye C., Hudson C., Stan R., Cebon J.S.;
RT   "The Ludwig Institute for Cancer Research Melbourne melanoma cell line
RT   panel.";
RL   Pigment Cell Melanoma Res. 26:597-600(2013).
//
RX   PubMed=27852308; DOI=10.1186/s12943-016-0554-y;
RA   Andrews M.C., Cursons J., Hurley D.G., Anaka M., Cebon J.S.,
RA   Behren A., Crampin E.J.;
RT   "Systems analysis identifies miR-29b regulation of invasiveness in
RT   melanoma.";
RL   Mol. Cancer 15:72.1-72.20(2016).
//