ID   H4-C99
AC   CVCL_U993
SY   H4-APP-C99
DR   BTO; BTO:0005095
DR   Wikidata; Q54872132
RX   PubMed=20143425;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Transfected with: HGNC; 620; APP (with p.Met1_Met671del = C99).
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C60781; Astrocytoma
DI   ORDO; Orphanet_94; Astrocytoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1239 ! H4
SX   Male
AG   37Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 29-06-23; Version: 10
//
RX   PubMed=20143425; DOI=10.1002/jnr.22356;
RA   Chae S.S., Yoo C.B., Jo C., Yun S.-M., Jo S.A., Koh Y.H.;
RT   "Caspases-2 and -8 are involved in the
RT   presenilin1/gamma-secretase-dependent cleavage of amyloid precursor
RT   protein after the induction of apoptosis.";
RL   J. Neurosci. Res. 88:1926-1933(2010).
//