Cellosaurus cell line SK-MEL-27-1 (CVCL

Cross-references
Cell line name	SK-MEL-27-1
Synonyms	SKMEL-27-1
Accession	CVCL_U913
Resource Identification Initiative	To cite this cell line use: SK-MEL-27-1 (RRID:CVCL_U913)
Comments	From: Memorial Sloan Kettering Cancer Center; New York; USA.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=21725359).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_6030 (SK-MEL-27)
Sex of cell	Female
Age at sampling	52Y
Category	Cancer cell line
Publications	PubMed=21725359; DOI=10.1038/onc.2011.250; PMCID=PMC3267014 Xing F., Persaud Y., Pratilas C.A., Taylor B.S., Janakiraman M., She Q.-B., Gallardo H.F., Liu C., Merghoub T., Hefter B.E., Dolgalev I., Viale A.J., Heguy A., de Stanchina E., Cobrinik D., Bollag G., Wolchok J.D., Houghton A.N., Solit D.B. Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring (V600E)BRAF. Oncogene 31:446-457(2012)
Cell line databases/resources	cancercelllines; CVCL_U913
Encyclopedic resources	Wikidata; Q54954000
Polymorphism and mutation databases	Cosmic; 1669142
Entry history
Entry creation	16-Apr-2014
Last entry update	19-Dec-2024
Version number	12