ID   ITM-E6/E7-ST
AC   CVCL_U246
SY   ITM-E6E7-ST; ITME6E7ST
DR   EFO; EFO_0002063
DR   GEO; GSM42178
DR   GEO; GSM42179
DR   Wikidata; Q54898366
RX   PubMed=16079833;
CC   Population: Caucasian.
CC   Genetic integration: Method=Transduction; Gene=HGNC; 6840; MAP2K1 (Note=Fused to a modified hormone-binding domain of ER = MEK-ER).
CC   Genetic integration: Method=Transduction; Gene=HGNC; 11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Fetal lung; UBERON=UBERON_0005597.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_U244 ! ITM
SX   Female
AG   16FW
CA   Transformed cell line
DT   Created: 03-02-14; Last updated: 10-09-24; Version: 12
//
RX   PubMed=16079833; DOI=10.1038/436642a;
RA   Collado M., Gil J., Efeyan A., Guerra C., Schuhmacher A.J.,
RA   Barradas M., Benguria A., Zaballos A., Flores J.M., Barbacid M.,
RA   Beach D.H., Serrano M.;
RT   "Tumour biology: senescence in premalignant tumours.";
RL   Nature 436:642-642(2005).
//