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Cellosaurus ITM (CVCL_U244)

[Text version]
Cell line name ITM
Accession CVCL_U244
Resource Identification Initiative To cite this cell line use: ITM (RRID:CVCL_U244)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=HGNC; 6840; MAP2K1 (Note=Fused to a modified hormone-binding domain of ER = MEK-ER).
Genetic integration: Method=Transduction; Gene=HGNC; 11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Fetal lung; UBERON=UBERON_0005597.
Cell type: Fibroblast of lung; CL=CL_0002553.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_U243 (ITV)
Children:
CVCL_U245 (ITM-E6/E7)CVCL_U246 (ITM-E6/E7-ST)CVCL_U247 (ITM-ST)
Sex of cell Female
Age at sampling 16FW
Category Telomerase immortalized cell line
Publications

PubMed=16079833; DOI=10.1038/436642a
Collado M., Gil J., Efeyan A., Guerra C., Schuhmacher A.J., Barradas M., Benguria A., Zaballos A., Flores J.M., Barbacid M., Beach D.H., Serrano M.
Tumour biology: senescence in premalignant tumours.
Nature 436:642-642(2005)

Cross-references
Encyclopedic resources Wikidata; Q54898364
Experimental variables resources EFO; EFO_0002061
Gene expression databases GEO; GSM42104
GEO; GSM42170
Entry history
Entry creation03-Feb-2014
Last entry update10-Sep-2024
Version number11