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Cellosaurus A2780-M (CVCL_TZ68)

[Text version]
Cell line name A2780-M
Accession CVCL_TZ68
Resource Identification Initiative To cite this cell line use: A2780-M (RRID:CVCL_TZ68)
Comments Population: African American.
Characteristics: Compared to the parent cell line, has high invasiveness and motility.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; 795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0134 (A2780)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=30046596

Markers:
AmelogeninX
CSF1PO10,11
D2S133821,22
D3S135814,16
D5S81811,12
D6S104311,19
D7S82010
D8S117915,17
D12S39118,19,20
D13S31712,13
D16S53911,13
D18S5116,18,19
D19S43312
D21S1128
FGA19,24
Penta D9,10
Penta E10,13
TH016
TPOX8,10
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=30046596; DOI=10.1155/2018/3972534; PMCID=PMC6036838
Jiang R.-B., Cheng G.-P., Zheng Z.-G., Ni M.-W., Wan D.-Y., Feng J.-G., Gu L.-H.
Establishment and characterization of a highly metastatic ovarian cancer cell line.
BioMed Res. Int. 2018:3972534.1-3972534.9(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_TZ68
Encyclopedic resources Wikidata; Q93311561
Entry history
Entry creation13-Nov-2018
Last entry update05-Oct-2023
Version number10