Cellosaurus cell line ND35367 (CVCL

Cellosaurus ND35367 (CVCL_T845)

Cross-references
Cell line name	ND35367
Synonyms	ND35367C; ND35367F
Accession	CVCL_T845
Resource Identification Initiative	To cite this cell line use: ND35367 (RRID:CVCL_T845)
Comments	Population: Caucasian. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:18618; LRRK2; Simple; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Homozygous (NHCDR=ND35367).
Disease	Parkinson disease 8, autosomal dominant (NCIt: C198605) Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_A9R0 (ND32948)
Sex of cell	Male
Age at sampling	79Y
Category	Induced pluripotent stem cell
Publications	PubMed=26651604; DOI=10.1016/j.stemcr.2015.11.004; PMCID=PMC4682343 Schwab A.J., Ebert A.D. Neurite aggregation and calcium dysfunction in iPSC-derived sensory neurons with Parkinson's disease-related LRRK2 G2019S mutation. Stem Cell Reports 5:1039-1052(2015) PubMed=27264186; DOI=10.1016/j.celrep.2016.05.022 Lin L., Goke J., Cukuroglu E., Dranias M.R., VanDongen A.M.J., Stanton L.W. Molecular features underlying neurodegeneration identified through in vitro modeling of genetically diverse Parkinson's disease patients. Cell Rep. 15:2411-2426(2016)
Cell line collections (Providers)	Coriell; ND35367 - Discontinued NHCDR; ND35367
Cell line databases/resources	SKIP; SKIP001369 SKIP; SKIP004684
Biological sample resources	BioSample; SAMN00805709
Encyclopedic resources	Wikidata; Q54929852
Entry history
Entry creation	03-Feb-2014
Last entry update	19-Dec-2024
Version number	21