ID   W12 [Human keratinocyte]
AC   CVCL_T290
DR   Wikidata; Q54993456
RX   PubMed=2467886;
RX   PubMed=7707525;
RX   PubMed=16505361;
CC   Virology: At early passages contains about 100 HPV16 episomes per cell (PubMed=7707525).
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Donor information: Established from a patient suffering from a low-grade squamous intraepithelial lesion (LG-SIL) (PubMed=2467886).
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   22Y
CA   Transformed cell line
DT   Created: 03-02-14; Last updated: 10-09-24; Version: 16
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RX   PubMed=2467886; DOI=10.1002/ijc.2910430422;
RA   Stanley M.A., Browne H.M., Appleby M., Minson A.C.;
RT   "Properties of a non-tumorigenic human cervical keratinocyte cell
RT   line.";
RL   Int. J. Cancer 43:672-676(1989).
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RX   PubMed=7707525; DOI=10.1128/JVI.69.5.2989-2997.1995; PMCID=PMC188998;
RA   Jeon S., Allen-Hoffmann B.L., Lambert P.F.;
RT   "Integration of human papillomavirus type 16 into the human genome
RT   correlates with a selective growth advantage of cells.";
RL   J. Virol. 69:2989-2997(1995).
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RX   PubMed=16505361; DOI=10.1073/pnas.0600078103; PMCID=PMC1383496;
RA   Pett M.R., Herdman M.T., Palmer R.D., Yeo G.S.H., Shivji M.K.K.,
RA   Stanley M.A., Coleman N.;
RT   "Selection of cervical keratinocytes containing integrated HPV16
RT   associates with episome loss and an endogenous antiviral response.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:3822-3827(2006).
//