ID   HAP1 CHCHD10 (-) 3
AC   CVCL_SI77
SY   HZGHC005043c003; CHCHD10 knockout cell line 1bp deletion
DR   cancercelllines; CVCL_SI77
DR   Horizon_Discovery; HZGHC005043c003
DR   Wikidata; Q54873390
RX   PubMed=37767023;
CC   Group: Haploid karyotype cell line.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 15559; CHCHD10.
CC   Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3174; Chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_Y019 ! HAP1
SX   Male
AG   40Y
CA   Cancer cell line
DT   Created: 14-05-18; Last updated: 30-01-24; Version: 10
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RX   PubMed=37767023; DOI=10.12688/f1000research.133479.2;
RA   Ayoubi R., Alshafie W., Southern K., McPherson P.S., Laflamme C.;
RT   "The identification of high-performing antibodies for
RT   coiled-coil-helix-coiled-coil-helix domain containing protein 10
RT   (CHCHD10) for use in western blot, immunoprecipitation and
RT   immunofluorescence.";
RL   F1000Research 12:403.1-403.8(2023).
//