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Cellosaurus NOU-1 (CVCL_S912)

[Text version]
Cell line name NOU-1
Synonyms Nou-1; NOU1; AG13904
Accession CVCL_S912
Resource Identification Initiative To cite this cell line use: NOU-1 (RRID:CVCL_S912)
Comments Part of: MD Anderson Cell Lines Project.
Omics: Protein expression by reverse-phase protein arrays.
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.
Sequence variations
  • Gene deletion; HGNC; 9588; PTEN; Zygosity=Homozygous (PubMed=20944090).
Disease Endometrial adenocarcinoma (NCIt: C7359)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 52Y
Category Cancer cell line
Web pages https://tcpaportal.org/mclp/
Publications

PubMed=12419584; DOI=10.1016/S0165-4608(01)00658-6
Faruqi S.A., Satyaswaroop P.G., LiVolsi V.A., Deger R.B., Noumoff J.S.
Establishment and characterization of a poorly differentiated lethal human endometrial carcinoma cell line (NOU-1) with karyotype 46,XX.
Cancer Genet. Cytogenet. 138:44-49(2002)

PubMed=20944090; DOI=10.1126/scitranslmed.3001538
Dedes K.J., Wetterskog D., Mendes-Pereira A.M., Natrajan R., Lambros M.B., Geyer F.C., Vatcheva R., Savage K., Mackay A., Lord C.J., Ashworth A., Reis-Filho J.S.
PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors.
Sci. Transl. Med. 2:53ra75.1-53ra75.8(2010)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections (Providers) Coriell; AG13904
Cell line databases/resources CLO; CLO_0022358
Encyclopedic resources Wikidata; Q54930929
Polymorphism and mutation databases Cosmic; 2030480
Entry history
Entry creation03-Feb-2014
Last entry update29-Jun-2023
Version number14